Patents & translation

Turning computational ideas into technologies.

Selected intellectual property and translational technology areas involving C3PH investigators and academic collaborators.

Prediction of stent expansion for treatments

US12609207B2 · Granted patent · April 21, 2026

AI-enabled prediction of coronary stent expansion using pre-stent intravascular imaging, lumen segmentation, and calcified plaque characterization to optimize procedural planning and treatment outcomes.

Interventional Cardiology Intravascular Imaging CWRU Collaboration

Prediction of stent expansion using finite element modeling and machine learning

US20240169524A1 · Published application · May 23, 2024

Computational framework integrating intravascular imaging, finite element modeling, treatment simulations, and machine learning to estimate stent effectiveness and procedural response.

Finite Element Modeling Machine Learning Interventional AI Case Western Reserve University

Prediction of major adverse cardiovascular events from AI analysis of pericoronary adipose tissue

US12573036B2 · Granted patent · March 10, 2026

AI-derived analysis of pericoronary adipose tissue and CT imaging biomarkers for prediction of future cardiovascular events and precision prevention strategies.

MACE Prediction CT Radiomics Precision Prevention Cardiovascular AI

Deep-learning-based hepatic fat assessment

US12530770B2 · Granted patent · January 20, 2026

Automated liver and spleen segmentation approaches for scalable hepatic fat quantification and cardiometabolic phenotyping from routine imaging studies.

Deep Learning Liver Fat AI Cardiometabolic Imaging CWRU Collaboration

Digitized imaging data for patient management and obstructive CAD analysis

US20260038116A1 · Published application · February 5, 2026

AI-enabled analysis of segmented non-contrast CT imaging data to support obstructive coronary artery disease characterization and patient management.

CAD Detection CT Analytics Patient Management Clinical AI

Medical analysis using spatiotemporal analysis and transformer-based models

US20250118435A1 · Published application · April 10, 2025

Transformer-based and spatiotemporal deep learning architectures for predictive analysis from anatomic video sequences and longitudinal imaging data.

Transformers Video AI Deep Learning Emory Collaboration

Risk prediction of heart failure

US20250217970A1 · Published application · July 3, 2025

AI-enabled extraction of pathophysiologic imaging features from clinical imaging datasets to predict incident heart failure and downstream cardiovascular outcomes.

Heart Failure Risk Prediction Imaging AI Precision Cardiology

Major adverse cardiovascular event risk prediction from comprehensive CT analysis

US20240321461A1 · Published application · September 26, 2024

Systems and methods for predicting cardiovascular events using AI analysis of CT calcium score imaging, imaging biomarkers, and multimodal radiomic features.

MACE Coronary Calcium Radiomics AI Risk Prediction

Linked identifiers distinguish granted patent publications from published applications. Publication type is not a statement of current enforceability or licensing availability. Records reviewed October 22, 2026; rights and licensing are handled by the relevant institutions.

Technology partnerships

Explore the path to translation.

Discuss research collaborations, validation studies, and technology-specific inquiries with C3PH.

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